Advocates of sanctions argue that they are having a crippling effect on the Iranian economy.

Yet, however crippling the effect of sanctions might be, they will not bring the regime to surrender its nuclear program.

It's a crippling time.

Cause crippling throughout the world.

Clearly, insufficient funds to maintain operations funded from committed extrabudgetary sources have a negative, and sometimes crippling, effect on the operations of other centres.

Solomon Islands' debt level remains crippling.

The civil strife which many African countries have had to cope with have also had a crippling effect on economic activity through damage to infrastructure.

The people of Gaza are living under a crippling blockade.

My fear of making another mistake is crippling my progress.

Moreover, when it is borne in mind that debt servicing obligations are estimated at about 30 per cent of the value of our exports, the crippling effect on our economies becomes apparent.

They included economically crippling curfews and closure of areas of Palestinian habitation.

When these swaps were activated, the banks would incur potentially further crippling losses.

The crippling external debt is one of the major obstacles for developing countries.

The debt burden destroyed consumer confidence and undermined the banking system, crippling the economy.

For nations that depend on trade, the sharp drop in exports this year was crippling.

Where to start , what to talk about ? The crippling electricity shortages, affecting hospitals as well as civilians?

That might seem crazy, especially given the likelihood of another round of economically crippling sanctions following the bombardment.

We can enhance the efficiency and legitimacy of globalization by supporting rather than crippling democratic procedures at home.

The socio economic crisis in the developing countries has been further exacerbated by the crippling burden of debt.

Honda has offered its transmission factory workers in China a 24 wage increase to head off a crippling strike.

The current crippling impact of continually rising energy costs on our fragile economies is a current case in point.

Debt levels remain crippling, amounting to more than 100 per cent of the gross domestic product of the Solomon Islands.

The continuing failure to release surplus lands is crippling local efforts to address the land needs of our civilian community.

Effect

Yet, however crippling the effect of sanctions might be, they will not bring the regime to surrender its nuclear program. The most for which one can hope is that sanctions enhance the chances of regime change by reawakening popular protest, thereby triggering an Iranian version of the Arab Spring.

And, while Tunisia s situation seems to be the most promising, a crippling investment shortfall is threatening to derail reform efforts there.

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That type of stochastic effect is called a hereditary effect.

As long as crippling economic sanctions remain in place, the government will be unable to have its yellowcake and eat it, too.

Gaucher s disease, for example, is a rare crippling genetic condition that, in its more severe forms, usually killed its victims in childhood.

Over several decades, a succession of civilian military dictatorships in third world countries incurred massive debts, which are currently crippling these countries.

The crippling effects of the sanctions on development, viewed in the broadest sense, in many ways equal those caused by war devastation.