Some 50 million people are infected with tubercle bacilli that are MDR.

This places the tubercle bacillus second only to human immunodeficiency virus (HIV) on the list of top microbial killers.

Moreover, the tubercle bacillus engages in trench warfare, gaining resistance to conventional antibiotics and canonical vaccination approaches, as well as delaying diagnosis and determination of drug sensitivity.

In anatomy, the term tubercle may describe a round nodule, small eminence, or warty outgrowth found on bones or skin, or, in cases of tuberculosis, in the lungs.

Sometimes the pulse cannot be taken at the wrist and is taken at the elbow (brachial artery), at the neck against the carotid artery (carotid pulse), behind the knee (popliteal artery), or in the foot dorsalis pedis or posterior tibial arteries.